一、个人基本情况
段硕,内蒙古赤峰市人,中国致公党党员,副教授。西南大学植物病理学博士,美国佛罗里达大学博士后,园艺学/生物医学工程专业硕导。联系邮箱:shuoduan@gnnu.edu.cn
二、主要研究方向
主要从事柑橘细菌性病害可持续绿色防控技术与体系研究,研究方向涵盖病原致病分子机理解析、抗耐病砧木种质创制、基于AI模型的防控病害产物挖掘与应用。
三、主要学术成果
近5年发表论文 (Corresponding author*, First author#)
1. Li, M#., Qin, HK#., Hu, YD#., Liao, FJ., Ouyang, ZG., Qin, BQ., Fan, ZR., Li, MZ., Mao, YP., Chen, H., Duan, S*. (2026). Ubiquitinationdriven proteostasis remodeling underlies oxidative stress and actin degradation in citrus huanglongbing. Plant Physiology. 202;202(1): 1-18.
2. Duan, S., Jiao, ZY., Lyu, HL., Li, M*., Chen, H*. (2026). Immune activation drives citrus Huanglongbing. Trends in Plant Science. doi: 10.1016/j.tplants.2026.08.009
3. Luo, RF., Zhang, SY., Wu, YX., Jiao, ZY., Bao, ML., Lan, YT., Zhang, TT., Zeng, RY., Yusuf, A., Zhang, YZ., Li, M., Duan, S*. (2026). Bacillus velezensis RF2 Rescued from Citrus Phyllosphere: Dual Mechanisms and Broad-Spectrum Activity for Controlling Citrus Bacterial Canker. Microorganisms. 6;14(1): 121
4. Zhang, SY., Luo, RF., Wu, YX., Zhang, TT., Yusuf, A., Wang, N., Li, M., Duan, S*. (2025). Establishment and application of high-pressure propagation breeding (HPPB)-mediated genetic transformation system in citrus rootstocks. Plant Biotechnology Journal, 23(7):2790-2792.
5. Yusuf, A., Li, M., Zhang, SY., Ajibade, F.O., Luo, RF., Wu, YX., Zhang, TT., Ugya, AY., Zhang, Y., Duan, S*. (2025). Harnessing plant–microbe interactions: Strategies for enhancing resilience and nutrient acquisition for sustainable agriculture. Frontiers in Plant Science, doi: 10.3389/fpls.2025.1503730
6. Guo, B., Duan, S#., Liu, F., & Fu, Z. Q. (2023). A vigilant gliding bird protects plants. Trends in biochemical sciences, 47(10), 819–821.
7. Wang, Y., Duan, S#., Xu, J., Long, YF., Zhang, SY., Li, SX., Wu, LJ., Zhang, YZ. (2023). Comparison of the colonization ability of Burkholderia strain B23 in the citrus rhizoplane and rhizosphere and assessment of the underlying mechanisms using full-length 16S rDNA amplicon and metatranscriptomic analyses, Microbial Biotechnology. 16(8):1657-1670.
8. Ma, H., Meng, X., Xu, K., Li, M., Gmitter, F. G., Jr, Liu, N., Gai, Y., Huang, S., Wang, M., Wang, M., Wang, N., Xu, H., Liu, J., Sun, X., Duan, S*. (2022). Highly efficient hairy root genetic transformation and applications in citrus. Frontiers in plant science, 13, 1039094.
9. Li, M., Qin, HK., Long, YF., Cheng, MQ., Li, L., Huang, AJ., Wang, N., Duan, S*. (2022). Field Deployable Candidatus Liberibacter asiaticus Detection Using Recombinase Polymerase Amplification Combined with CRISPR-Cas12a, JoVE Journal. doi:10.3791/64070
10. Duan, S., Xu, Z., Li, X. Y., Liao, P., Qin, H. K., Mao, Y. P., Dai, W. S., Ma, H. J., & Bao, M. L. (2022). Dodder-transmitted mobile systemic signals activate a salt-stress response characterized by a transcriptome change in Citrus sinensis. Frontiers in plant science, 13, 986365.
11. Long, Y., Luo, R., Xu, Z., Cheng, S., Li, L., Ma, H., Bao, M., Li, M., Ouyang, Z., Wang, N., & Duan, S*. (2022). A Fluorescent Reporter-Based Evaluation Assay for Antibacterial Components Against Xanthomonas citri subsp. citri. Frontiers in microbiology, 13, 864963.
12. Duan, S., Long, Y., Cheng, S., Li, J., Ouyang, Z.,Wang, N. (2022). Rapid Evaluation of the Resistance of Citrus Germplasms Against Xanthomonas citri subsp. citri. Phytopathology, 112(4), 765–774.
13. Liu, C., Zhang, J., Song, M., Wang, X., Lv, W., Ding, X., Zhu, J., Deng, Y., Ge, Y., Wu, J., Handique, U., Duan, S., Shen, Y., Luo, F., Xiao, S., & Zhou, X. (2025). Propionate serves as a degradable control agent of citrus canker by acidifying cytoplasm and depleting intracellular ATP in Xanthomonas citri. mBio, 16(6), e0064225. https://doi.org/10.1128/mbio.00642-25
14. Gill RA., Li XL., Duan S., Xing Q., Xing RM. (2024) Citrus threat huanglongbing (HLB) - Could the rootstock provide the cure? Frontiers in plant science., doi.org/10.3389/fpls.2024.1330846
15. Lin, H., Liang, Y., Kaliaperumal, K., Xiong, Q., Duan, S., Jiang, Y., Zhang, J. (2023) Linoleic acid from the endophytic fungus Diaporthe sp. HT-79 inhibits the growth of Xanthomonas citri subsp. citri by destructing the cell membrane and producing reactive oxygen species (ROS). Pesticide Biochemistry and Physiology. 192:105423.
16. Hu, W., Zhao, CF., Zheng, RK., Duan, S., Lu, ZJ., Zhang, ZX., Yi, L., Zhang, N. (2023) Serratia marcescens induces apoptosis in Diaphorina citri gut cells via reactive oxygen species‐mediated oxidative stress, Pest management Science., doi: 10.1002/ps.7787
17. Duan, S., Jia, H., Pang, Z., Teper, D., White, F., Jones, J., Zhou, C., & Wang, N. (2018). Functional characterization of the citrus canker susceptibility gene CsLOB1. Molecular plant pathology, 19(8), 1908–1916. (Content of PhD thesis)
科研经费项目
1. 国家青年科学基金项目, CsPDT 基因调控溃疡病表型形成机制的研究, 2021.01- 2023.12, 主持
2. 江西省杰出青年基金项目(20232ACB215007), 维管系统介导柑橘遗传转化根系提升植株抗病性的研究, 2023.07-2026.07, 主持
3. 江西省农业关键核心技术攻关专项(JXNK2026), 柑橘抗黄龙病砧木培育其田间应用研究, 2026.06 -2029.12, 主持
4. 江西省自然科学基金基础研究计划(20252BAC240592), 柑橘溃疡病致病效应蛋白PthA4影响叶内微生物稳态并触发柑橘宿主招募生防菌Bac-1的机制研究, 2026.01-2028.01, 主持
5. 江西省农业关键核心技术攻关专项(JXNK202304-04), 柑橘抗黄龙病砧木培育和提升研究, 2023.6 -2025.12, 主持
6. 江西省重大科技研发专项(S2019ZDYFB0031), 柑橘黄龙病和溃疡病致病机理及其综合防控技术研究与示范.2019.03-2024.09
7. 院校联合横向课题(HX-520650), 三种丙酸盐对柑橘溃疡病的田间方式效果, 2024.09-2026.12, 主持
8. 企业联合横向课题(HX-520937), 寡糖类生物源农药的杀溃疡病菌活性研究, 2022.07-2023.07, 主持
9. 美国农业部研究计划, Consequences of genome editing the susceptibility gene CsLOB1 for citrus bacterial canker,2016.08-2019.07
部分申请授权专利
1. 一种抗菌肽活性预测方法、系统及应用[P], 202610611892.1
2. 一种快速筛选柑橘黄龙病抗菌肽和小分子化合物的方法及其应用[P], CN202511278799.5
3. 一种快速筛选柑橘黄龙病生防菌的方法及其应用[P], CN202511279869.9
4. 一种快速获得柑橘砧木遗传转化根系的方法及其应用[P], CN119709824A
5. 一种高通量测定柑橘溃疡病菌杀菌剂活性的方法[P], CN114350741 B
6. 一种芸香科植物的遗传转化体系、遗传转化方法和应用[P], CN114657207A
7. 一种基于RPA-CRISPR-Cas12a体系检测黄龙病菌的方法[P], CN202210732514.0
8. 一种快速评估柑橘品种对溃疡病抗性的方法[P], CN202111567079.2
国际报告交流情况
1. Duan, S. Exploring antimicrobial peptides for the control of citrus Huanglongbing disease- a strategy for genetic transformation and evaluation of disease resistance in rootstocks, 15th International citrus congress .(2024), 济州岛, 韩国
2. Duan, S. Direct evidence of CsLOB1 being the susceptibility gene of citrus canker caused by Xanthomonas citri, American Phytopathological Society Annual Meeting (2017),德克萨斯圣安东尼奥, 美国
3. Duan, S., Jia, HG., Gowda, S., Wang, N. Dissecting the function and downstream targets of CsLOB1 in citrus, Representation No: Effector Biology, 109-O, American Phytopathological Society Annual Meeting (2016), 佛罗里达州坦帕市,美国
4. Duan, S., Jia, HG., Siddrame, G., Jones, JB., Wang, N. Characterization of targets of PthA4 and their involvement in citrus canker development, Poster No: Molecular Aspects of Effectors and their Host Targets, Poster No: 681-P, American Phytopathological Society Annual Meeting (2015), 加利福尼亚州帕萨迪纳,美国
研究生培养情况
(指导省优毕业论文1篇,校优毕业论文4篇,校优本科毕业论文4篇)
龙云飞,2023届园艺专业硕士,福建农林大学博士,入职云南农业大学植物保护学院;
徐 洲,2024届生物医学工程专业硕士,已就职法雷奥汽车内部控制(深圳)有限公司;
张斯羽,2025届园艺专业硕士,目前攻读福建农林大学植物保护学院博士;
罗瑞芳,2026届园艺专业硕士,目前攻读扬州大学生物科学与技术学院博士;
焦子怡,2024级园艺专业硕士研究生在读;
兰宇婷,2025级生物医学工程专业硕士研究生在读。