一、个人简介
余海中，安徽铜陵人，博士，副教授，硕士生导师，江西省科技特派员，江西省植物保护学会常务理事，江西省生物化学与分子生物学理事，中国生物化学与分子生物学学会、国际“柑橘黄龙病和韧皮部细菌病害系统学会（ISCHLP）”和江西省园艺学会会员。目前主要围绕柑橘病虫害的防控开展相关研究，主持国家自然科学基金、国家重点研发计划子课题和江西省自然科学基金等，2023年获批江西省赣鄱俊才主要学科技术带头人青年项目，2023年荣获江西省科技进步二等奖，2024年入选赣南师范大学“赣江之星”。已在Pest Management Science、International Journal of Biological Macromolecules、Journal of Agricultural and Food Chemistry 和Insect Science等国际学术刊物上发表SCI论文42篇（单篇最高引用65次），《Pest Management Science》、《BMC Genomics》、《Insect Molecular Biology》和《Arthropod-Plant Interactions》等杂志特邀审稿人，并担任《Frontiers in Insect Science》杂志Associate editor和《植物医学》杂志青年编委。
E-mail：yuhaizhong1988@163.com；微信号：13965064692
热忱欢迎植物保护学、园艺学和生物科学相关专业学生报考课题组研究生。
二、受教育经历
2015年9月—2018年7月，安徽农业大学，生物化学与分子生物学，理学博士
2012年9月—2015年7月，安徽农业大学，特种经济动物饲养，农学硕士
2008年9月—2012年7月，安徽农业大学，纺织工程，工学学士
三、研究兴趣
1. 柑橘黄龙病菌与柑橘木虱博弈的分子机制（聚焦蛋白质泛素化修饰）；
2. 柑橘木虱-柑橘黄龙病-柑橘互作机理（聚焦唾液蛋白的功能）；
3. RNA农药的研发与应用（与其他单位合作）。
四、主持和参与的科研项目
1. CLas病菌调控柑橘木虱骨架蛋白泛素化促进病菌转运机制研究，赣鄱俊才支持计划-主要学科技术和技术带头人培养青年人才项目，2024.01-2026.12，30万，主持；
2. 江西省自然科学基金面上项目，20224BAB205012，柑橘木虱泛素结合酶UbcE2J2调控骨架蛋白MRLC2促进CLas病菌转运机制研究，2023-01—2025.12，10万，主持；
3. 国家自然科学基金地区项目，32260674，黄龙病菌分泌蛋白LepB介导柑橘木虱骨架蛋白的泛素化促进病菌转运机制研究，2023.01—2026.12，33万，主持；
4. 国家重点研发计划（子课题），2021YFD1400800，柑橘黄龙病灾变机制与可持续防控技术研究，2021.12—2024.12，95万，主持；
5. 江西省科技厅青年项目，20202BAB215004，柑橘木虱海藻糖酶基因的鉴定和生物学功能研究，2020.01—2022.12，6万，主持；
6. 江西省教育厅重点项目，GJJ180747，Toll信号通路介导的组织蛋白酶L和O在柑橘木虱先天性免疫中的分子机制，2019.01—2020.12，5万，主持；
7. 赣州市科技创新人才项目，柑橘木虱几丁质合成途径中海藻糖抑制剂的筛选及其在木虱防控中的应用，2020.01—2022.12，主持；
8. 国家自然科学基金面上项目，32272549，柑橘黄龙病菌SDEs介导柑橘木虱中肠上皮细胞囊泡转运机制研究，2023.01—2026.12，54万，第二参与人；
9. 国家自然科学基金地区项目，31960116，CLas病菌侵染柑橘木虱中肠及其调控UPS免疫逃避机制研究，2020.01—2023.12，40万，第二参与人；
10. 国家自然科学基金面上项目，31472148，BmNPV与宿主家蚕中肠及胞内蛋白互作的分子机制研究，2014.01—2018.12，80万，第三参与人。
五、 近年来部分科研成果
主要论文（*：通讯作者；#：共同一作）：
2025年：
1. Xiao-Fang Yuan #, Ai-Yun Wang #, Wen-Feng Kang, Ying-Xue Liu, Wei Chen, Xiao-Qiang Liu, Zhan-Jun Lu, Hai-Zhong Yu *. Functional characterization of a tyrosine hydroxylase in Diaphorina citri and utilization of SPc nanoarticle-wrapped dsRNA for pest cntrol. Pest Management Science, 2025, DOI: 10.1002/ps.70080. (中科院大类1区top, IF: 4.1).
2. Xiao-Jin Zhou #, Yi-Hong Zhang #, Can-Zhang #, Xiao-Fang Yuan, Men-Jun Yun, Lian-Jie Xie, Xiao-Qiang Liu, Wen-Feng Kang, Wei Chen, Ying-Xue Liu, Ai-Yun Wang, Zhan-Jun Lu *, Hai-Zhong Yu *. Diaphorina citri E3 ubiquitin ligase RNF115 inhibits CLas bacterial proliferation by targeting to the host histone H1. Insect Science, 2025, DOI 10.1111/1744-7917.70022. (中科院大类1区top, IF: 4.0).
3. Qian Li, Wan-Wei Hu, Ao Fang, Zhuo-Bing Wang, Xiao-Fang Yuan, Yue Sun, Zheng-Hui Zou, Nuo Chen, Tian-Xing Jing, Ying-Xue Liu, Wei Chen, Hai-Zhong Yu *, Zhan-Jun Lu *, Xiao-Qiang Liu *. Chemosensory protein 8 confers thiamethoxam resistance in Diaphorina citri. Pesticide Biochemistry and Physiology. 2025, 208, 106264. (中科院大类1区top, IF: 4.2).
2024年：
1. Xiao-Fang Yuan, Hong Zhong, Zhan-Jun Lu, Wei Chen, Ying-Xue Liu, Gu-Chun Zhou, Xiao-Qiang Liu *, Ming-Jie Deng *, Hai-Zhong Yu *. Integration analysis of transcriptome and 1H-NMR-based metabolome to reveal the toxicological effect of flupyrimin on Spodoptera litura. Pesticide Biochemistry and Physiology, 2024, doi.org/10.1016/j.pestbp.2024.106146 (中科院大类1区top, IF: 4.2).
2. Zhan-Jun Lu, Tao Xia, Can Zhang, Qing He, Shang-Cheng Fu, Xiao-Fang Yuan, Xiao-Qiang Liu, Ying-Xue Liu, Wei Chen, Long Yi, Hai-Zhong Yu *. Characterization of an RR-2 cuticle protein DcCP8 and its potential application based on SPc nanoparticle-wrapped dsRNA in Diaphorina citri. Pest Management Science, 2024, 10.1002/ps.8355 (中科院大类1区top, IF: 4.1).
3. Qin Zhang, Can Zhang, Hong Zhong, Qing He, Zhao-Ying Xia, Yu Hu, Yu-Xin Liao, Long Yi, Zhan-Jun Lu, Hai-Zhong Yu *. A Combinatorial Single-Molecule Real-Time and Illumina Sequencing Analysis of Postembryonic Gene Expression in the Asian Citrus Psyllid Diaphorina citri. Insects, 2024, 15, 391. (中科院大类2区, IF: 3.139).
2023年：
4. Lian-Jie Xie, Xiang-Dong Zeng, Muhammad Bial Amir, Xiao-Jin Zou, Jin-Fu Yuan, Hai-Zhong Yu *, Zhan-Jun Lu *, Wei Chen *. Clathrin heavy chain is involved in infection of Candidatus Liberibacter asiaticus in the host vector Diaphorina citri. Insect Science, 2023, DOI 10.1111/1744-7917.13305 (中科院大类1区top, IF: 4.0)
5. Wei Chen, Muhammad Bilal Amir, Yuan Liao, Hai-Zhong Yu, Wei-Yi He *, Zhan-Jun Lu *. New Insights into the Plutella xylostella Detoxifying Enzymes: Sequence Evolution, Structural Similarity, Functional Diversity, and Application Prospects of Glucosinolate Sulfatases. Journal of Agricultural and Food Chemistry, 2023, DOI: 10.1021/acs.jafc.3c03246. (中科院大类1区top, IF: 6.1)
6. Tao Xia, Yan Liu, Zhan-Jun Lu, Hai-Zhong Yu *. Natural Coumarin Shows Toxicity to Spodoptera litura by Inhibiting Detoxification Enzymes and Glycometabolism. International Journal of Molecular Sciences, 2023, 24, 13177 (中科院大类2区top, IF: 5.6).
7. Qin Zhang, Tao Xia, Ai-Yun Wang, Yan Liu, Ning-Yan Li, Long Yi, Zhan-Jun Lu, Hai-Zhong Yu *. Alternative splicing of chitin deacetylase 2 regulates chitin and fatty acid metabolism in Asian citrus psyllid, Diaphorina citri. Archives of Insect Biochemistry and Physiology, 2023, accepted. (中科院大类4区, IF: 2.2).
8. Xiu-Dao Yu, Hollie Marshall, Yan Liu, Yu Xiong, Xiang-Dong Zeng, Hai-Zhong Yu, Wei Chen, Gu-Chun Zhou, Bo Zhu, Laura Ross, Zhan-Jun Lu. Sex-specific transcription and DNA methylation landscapes of the Asian citrus psyllid, a vector of huanglongbing pathogens. Evolution, 2023, https://doi.org/10.1093/evolut/qpad036 (中科院大类2区top, IF: 4.171).
9. Jin-Bo Zhang, Xiao-Jin Zou, Qin Zhang, Ai-Yun Wang, Muhammad Bial Amir, Yi-Min Du, Xiao-Qiang, Liu, Wei Chen, Zhan-Jun Lu, Hai-Zhong Yu *. Quantitative ubiquitylome crosstalk with proteome analysis revealed cytoskeleton proteins influence CLas pathogen infection in Diaphorina citri. International Journal of Biological Macromolecules, 2023, 232, 123411 (中科院大类1区top, IF: 8.025).
2022年：
1. Jin-Bo Zhang, Zhan-Jun Lu, Hai-Zhong Yu *, Silencing of Glycogen Synthase Kinase 3 Significantly Inhibit Chitin and Fatty Acid Metabolism in Asian Citrus Psyllid, Diaphorina citri. International Journal of Molecular Sciences, 2022, 23, 9654 (中科院大类2区top, IF: 6.208).
2. Ying-Xue Liu, Lin-Bao Zhu, Zhe-Xiao Guo, Han-Dan Zhu, Zhi-Hao Huang, Hui-Hua Cao, Hai-Zhong Yu, Shi-Huo Liu, Jia-Ping Xu, Bombyx mori ferritin heavy-chain homolog facilitates BmNPV proliferation by inhibiting reactive oxygen species-mediated apoptosis. International Journal of Biological Macromolecules, 2022, 217, 842-852 (中科院大类1区top, IF: 8.025).
3. Hai-Zhong Yu, Long Yi *, Zhan-Jun Lu *, Silencing of chitin-binding protein with PYPV-rich domain impairs cuticle and wing development in the Asian citrus psyllid, Diaphorina citri. Insects, 2022, 13, 353 (中科院大类2区, IF: 3.139).
4. Ying Wang, Qin Zhang, Hai-Zhong Yu*, Functional analysis of a peptidoglycan recognition protein involved in the immune response in the common cutworm, Spodoptera litura. Archives of Insect Biochemistry and Physiology, 2022, 109, e21858 (中科院大类4区, IF: 2.454).
5. Hai-Zhong Yu#, Qin Zhang#, Zhan-Jun Lu*, Ming-Jie Deng*. Validamycin treatment significantly inhibits the glycometabolism and chitin synthesis in the common cutworm, Spodoptera litura. Insect Science, 2022, 29, 840-854. (中科院1区top, IF: 3.605).
2021年以前：
1. Jian-Chun Song, Zhan-Jun Lu, Long Yi *, Hai-Zhong Yu*, Physiological functions of a novel trehalose-6-phosphate synthase in Diaphorina citri revealed that by RNA interference and transcriptome. Insects, 2021, 12, 1074 (中科院大类2区, IF: 3.139).
2. Xiao-Qiang Liu, Hong-Bo Jiang, Jia-Yao Fan, Tian-Yuan Liu, Li-Wei Meng, Yi Liu, Hai-Zhong Yu, Wei Dou, Jin-Jun Wang. An odorant-binding protein of Asian citrus psyllid, Diaphorina citri, participates in the response of host plant volatiles. Pest Management Science, 2021, 77, 3068-3079. (中科院大类1区top, IF: 4.462).
3. Hai-Zhong Yu#, Yan-Xin Xie#, Jie Wang, et al. Integrated transcriptome sequencing and RNA interference reveals the molecular changes of Diaphorina citri exposure to validamycin, Insect Science, 2021, 28, 1690-1707. (中科院1区top, IF: 3.605)
4. Hai-Zhong Yu#, Yu-Ling Huang#, Zhan-Jun Lu*, et al. Inhibition of trehalase affects the trehalose and chitin metabolism pathways in Diaphorina citri (Hemiptera: Psyllid), Insect Science, 2021, 28, 718-734. (中科院1区top, IF: 3.605, 2024年入选Insect Science杂志高引论文).
5. Hai-Zhong Yu#, Ning-Yan Li#, Bing Li, et al. Immune functional analysis of chitin deacetylase 3 from the Asian citrus psyllid Diaphorina citri. International Journal of Molecular Sciences, 2020, 21, 64.
6. Hai-Zhong Yu#, Ning-Yan Li#, Xiang-Dong Zeng, et al. Transcriptome analysis of Diaphorina citri midgut responses to Candidatus Liberibacter asiaticus infection. Insects, 2020, 11, 171. (IF: 2.139)
7. Hai-Zhong Yu#, Ning-Yan Li#, Yan-Xin Xie, et al. Identification and functional analysis of two chitin synthase genes in the common cutworm, Spodoptera litura, Insects, 2020, 11, 253.
8. Hai-Zhong Yu, Yu-Ling Huang, Ning-Yan Li, et al. Potential roles of two Cathepsins genes, DcCath-L and DcCath-O in the innate immune response of Diaphorina citri. Journal of Asia-Pacific Entomology, 2019, 22: 1060-1069.
9. Hai-Zhong Yu, Jie Wang, Shang-Zhi Zhang, et al. Molecular characterization of Apolipophorin-Ⅲ gene in Samia cynthia ricini and its roles in response to bacterial infection. Journal of Invertebrate Pathology, 2018, 159, 6170.
10. Hai-Zhong Yu, Yan Ma, Shang-Zhi Zhang, et al. Comparative transcriptome analysis of ATP-binding cassette (ABC) transporter genes in eri-silkworm, Samia cynthia ricini in response to 1-deoxynojirimycin, Journal of Asia-Pacific Entomology, 2018: 168-178.
11. Hai-Zhong Yu, Xue-Yang Wang, Jia-Ping Xu*, et al. iTRAQ-based quantitative proteomics analysis of molecular mechanisms associated with Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic strains, Journal of Proteomics, 2017, 165, 35-50.
12. Hai-Zhong Yu, Shang-Zhi Zhang, Yan Ma, et al. Molecular Characterization and Functional Analysis of a Ferritin Heavy Chain Subunit from the Eri-Silkworm, Samia cynthia ricini, International Journal of Molecular Sciences, 2017.
13. Hai-Zhong Yu, Jia-Ping Yu*, Xue-Yang Wang, et al. Identification of four ATP-binding cassette transporter genes in Cnaphorina medinalis and their expression in response to insecticide treatment, Journal of Insect Science, 2017, 17, 1-8.
14. Hai-Zhong Yu, Ming-Hui Liu, Xue-Yang Wang, et al. Identification and expression profiles of chitin deacetylases genes in the rice leaf folder, Cnaphorina medinalis, Journal of Asia-Pacific Entomology, 2016, 19: 691-696.
15. Hai-Zhong Yu, De-Fu Wen, Wan-Lin Wang, et al. Identification of genes putatively involved in Chitin Metabolism and Insecticide Detoxification in the rice leaf folder (Cnaphalocrocis medinalis) larvae through transcriptome analysis, International Journal of Molecular Sciences, 2015, 16, 21873-21896.
16. Zhan-Jun Lu#, Yu-Ling Huang#, Hai-Zhong Yu*, et al. Silencing of the Chitin Synthase Gene Is Lethal to the Asian Citrus Psyllid, Diaphorina citri, International Journal of Molecular Sciences, 2019, 20, 3734.
17. Zhan-Jun Lu#, Hai-Zhong Yu#, Lan-Fang Mi#, et al. The effects of inarching Citrus reticular Blanco var. tangerine on the tree vigor, nutrient status and fruit quality of Citrus sinensis Osbeck ‘Newhall’ trees that have Poncirus trifoliata (L.) Raf. as rootstocks. Scientia Horticulturae, 2019, 256, 108600.
18. Zhan-Jun Lu#, Yan-Xin Xie#, Hai-Zhong Yu*, et al. Identification of an iron binding protein, ferritin heavy chain subunit and functional analysis, from swallowtail butterfly, Papilio xuthus. Archives of Insect Biochemistry & Physiology, 2019, 102, 1.
19. Zhan-Jun Lu#, Cheng-Hua Zhou#, Hai-Zhong Yu*, et al. Potential roles of insect Tropomyosin1-X1 isoform in the process of Candidatus Liberibacter asiaticus infection of Diaphorina citri, Journal of Insect Physiology, 2019, 114, 125-135 (IF: 2.862).
20. Dong-Qiong Fei#, Hai-Zhong Yu#, Jia-Ping Xu, et al. Isolation of ferritin and its interaction with BmNPV in the silkworm, Bombyx mori, Developmental and Comparative Immunology, 2018, 130-137.
21. Bing Li#, Hai-Zhong Yu#, Chong-Jun Ye, et al. Bombyx mori Seripin6 regulates prophenoloxidase activity and the expression of antimicrobial proteins, Gene, 2017, 610, 64-70. (IF: 2.638).
22. Xue-Yang Wang#, Hai-Zhong Yu#, Jia-Ping Xu*, et al. Comparative subcellular proteomics analysis of susceptible and near-isogenic resistant Bombyx mori (Lepidoptera) larval midgut response to BmNPV infection, Scientific Reports, 2017, 7, 45690.
23. Xue-Yang Wang#, Hai-Zhong Yu#, Lei Geng, et al. Comparative transcriptome analysis of Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic resistant strains, PLoS One, 2016, 11, e0155341.
24. Shang-Zhi Zhang#, Hai-Zhong Yu#, Ming-Jie Deng, et al. Comparative transcriptome analysis reveals significant metabolic alterations in eri-silkworm (Samia cynthia ricini) haemolymph in response to 1-deoxynojirimycin, PLoS One, 2018, 13, e0191080.
25. Azharuddin, Muhammad, Shahzad, Toufeeq, Hai-Zhong Yu, et al. Molecular characterization of two mitogen-activated protein kinases: p38 MAP kinase and ribosomal S6 kinase from Bombyx mori (Lepidoptera: Bombycidae), and insight into their roles in response to BmNPV infection, Journal of Insect Science, 2019, 19, 15.
26. Li-Ang Yang, Jie Wang, Shahzad, Toufeeq, Lin-Bao Zhu, Shang-Zhi Zhang, Ling-Ling You, Pei Hu, Hai-Zhong Yu, Kang Zhao, Jia-Ping Xu, Identification of FerLCH, isolation of ferritin and functional related to interaction with pathogens in Eri-silkworm, Samia cynthia ricini, Archives of Insect Biochemistry and Physiology, 2020, 104, e21659.
申报的专利：
1. 发明人：余海中、张金波、方瑜婕、段硕、陈玮、卢占军、胡威、朱博、姚锋先、黄爱军、苏华楠、彭婷、欧阳智刚、舒佳旺、刘佳阳，发明专利名称：一种获得CLas侵染柑橘木虱虫体的方法；时间：2022.05.013；专利号：202210504089.X.
2. 发明人：卢占军、曾祥东、张金波、余海中、方瑜婕、胡威、陈玮、黄爱军、彭婷、姚锋先、邹小金、谢廉颉、汪和贵、舒佳旺，发明专利名称：柑橘木虱泛素结合酶E2J2基因在防控柑橘黄龙病中的应用；时间：2022.05.07；专利号：ZL202210490662.6.（已授权）
3. 发明人：张金波，方瑜婕，余海中，汪和贵，刘淑婷，黄爱军，刘佳阳，赖子俊，卢占军，舒佳旺，曹鑫磊，曾祥东；实用新型专利名称：一种对照实验用刺吸式昆虫饲养装置；申请时间：2022.5.19；专利号：ZL202221218071.5. (已授权)
4. 发明人：卢占军，邹俊丞，钟八莲，饶敏，苏华楠，余海中，王年，乔宁，邝敏；发明专利名称：一种基于树皮韧皮部的脐橙黄龙病近红外检测模型建立方法；申请时间：2018.12.27；专利号：ZL201811611126.7. (已授权)
5. 发明人：余海中，卢占军，谢妍馨，李宁艳，喻修道，黄爱军，易龙，苏华楠，钟八莲；发明专利名称：柑橘木虱几丁质结合蛋白Chitinase-like ENO3及其编码基因和应用；国际专利申请号：PCT/CN2020/100775；国际申请日：2020年7月8日；发文日：2021年4月9日。(已授权)
6. 发明人：邹小金，付尚成，刘俊言，刘洁，舒佳旺，谢廉颉，余海中，卢占军，陈玮，汪和贵，郭亮，金子玲，曹鑫磊，王旷；发明专利名称：一种柑橘木虱泛素连接酶RNF115基因、编码蛋白及其在防控黄龙病中的应用；申请时间：2023.12.21；申请号：2023117656356；
7. 付尚成，刘俊言，刘洁，舒佳旺，金子玲，曹鑫磊，王旷，邹小金，张金波，余海中，卢占军，刘小强，陈玮，汪和贵，郭亮；一种柑橘木虱泛素连接酶E3TM129 基因、编码蛋白及其在防控黄龙病中的应用；申请时间：2023.12.21；申请号：2023117749030；
8. 刘妍，余海中，卢占军，刘映雪，刘小强，陈玮，张金波，邹小金，张灿，何青，钟鸿，舒佳旺；柑橘木虱myosin 调节蛋白轻链2 在防控黄龙病菌中的应用；申请时间：2024.02.28；申请号：2024102181749；
9. 张灿，余海中，夏涛，钟鸿，何青，舒佳旺，卢占军，陈玮，刘小强，刘映雪；沉默DcCP8基因在防治柑橘木虱中的应用；申请时间：2024.03.08；申请号：2024102687981。
六、指导本科生获奖
1. 2025年，指导2023级本科生张乙弘等荣获中国国际大学生创新大赛江西省金奖1项，银奖2项，铜奖2项；
2. 2025年，指导2022级本科生张灿等荣获第十九届“挑战杯”江西省大学生课外学术科技作品竞赛特等奖；
3. 2025年，指导2023级本科生张乙弘荣获第三届江西省大学生职业规划大赛银奖；
4. 2025年，指导2022级本科生钟鸿荣获生命科学竞赛（创新创业类）全国三等奖；
5. 2025年，指导2022级本科生夏照莹荣获生命科学竞赛（科学探究类）全国三等奖；
6. 2024年，指导2022级本科生张灿等荣获中国国际大学生创新大赛国赛铜奖2项，江西省金奖2项；
7. 2024年，指导2022级本科生张灿等荣获第十四届 “挑战杯”江西省大学生创业计划竞赛铜奖；
8. 2022年，指导2022年全国大学生生命科学竞赛（科学探究类）江西赛区三等奖；
9. 2019年，指导2018级研究生谢妍鑫获得江西省园艺学会奔象杯“优秀学术论文”一等奖。
七、已毕业的研究生去向
2022级袁小芳（华东师范大学科研助理）
2021级夏涛（西南大学在读博士）
2021级邹小金（福建农林大学在读博士）
2020级张金波（东南大学在读博士）
2019级宋建春（赣州市烟草公司会昌分公司）
